Blog: The Quad-Cycle Hypothesis

Blog: The quad-cycle hypothesis – a(nother) “new” theory of type 2 diabetes

Could there be FOUR key cycles involved in the development of type 2 diabetes?

We know that the liver, pancreas and muscles play important roles in metabolic health – but what about our body fat?

In his latest blog, Dr Sean Wheatley, Science and Research Lead at X-PERT Health, introduces the quad-cycle hypothesis, exploring how dysfunction in fat tissue may contribute to insulin resistance and type 2 diabetes.

The good news? Understanding these interconnected cycles highlights practical ways to support metabolic health:

✅ Reducing excess body fat
✅ Managing carbohydrate intake to individual tolerance
✅ Building and maintaining muscle mass

Could there be FOUR key cycles involved in the development of type 2 diabetes?

Discover how these four systems interact and why understanding them could help us better manage type 2 diabetes.

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